The distribution of cadmium within organes was determined following a single or multiple oral doses, and we specially studied retention of a Cd dose ingested after several weeks of treatment with Cd-Acetate. Before studying gastro-intestinal absorption, it appeared necessary to precise acute toxicity of orally administred cadmium. The absorption and the elimination of cadmium have been investigated in rats wistar after oral administration or after inhalation. Cadmium 109 maximum permissible concentration (author)Įxperimental study, in rat wistar, of cadmium distribution and elimination as a function of administration route. The in vitro labeling procedure with radioactive cadmium is a more rapid procedure than analyzing the element in the original sample. These fractions were identified by chemical analysis of cadmium as well as by radioactive labeling. Cadmium was found in two main fractions having apparent molecular weights of about 5 dalton. Cell extracts were labeled in vitro with radioactive 109 Cd.

The heavy metal had no influence on the growth of the fungus at this concentration. Hyphae from the edible mushroom Agaricus arvensis were grown in a liquid medium supplemented with 1 mg cadmium per litre. Identification of the cadmium binding compounds in Agaricus arvensis hyphae using 109Cd Correction based on using triated L-glucose in all of these experiments and calculating a correction factor for the concentration of cadmium The problem does not appear to be related to the use of the buffer or to adsorption of Cd onto glass. It was important to determine whether the procedure could be modified to correct this problem. The objective is to determine whether the buffer solution used in the membrane transport studies is causing precipitation of the cadmium or whether cadmium is being adsorbed by the glass.

An anomaly discovered in the liquid scintillation counting analysis of Cd- 109 which is not attributable to normal decay it consists of a significant decrease in the measured count rate of small amounts of sample. Recently the authors have used radiolabled cadmium- 109 to measure the transport of inorganic cadmium in renal proximal tubules. Liquid scintillation counting analysis of cadmium- 109 First method is based on precipitation of silver as In the present work we studied two methods for separation of 109 Cd from model solution of silver targets. Because of its relatively long half-life the time required for separation is also not an important factor, but its use as an X-ray source requires a very high radiochemical purity. The production of 109 Cd with proton beam via 109 Ag(p,n) 109 Cd reaction is ideal for the cyclotron U-150, since it is not required the change of the regime for the machine functioning. Irradiation of enriched 108 Cd target in nuclear reactor at neutron flux 1x10 14 nÂ Irradiation of enriched 107 Ag target in high-flux nuclear reactor at neutron flux 2x10 15 nÂ Proton bombardment of natural indium target with 96 MeV protons.

Bombardment of natural silver target via 109 Ag(p,n) 109 Cd reaction with 14 MeV protons. Bombardment of silver cyclotron target via 109 Ag(d,2n) 109 Cd reaction with 16 MeV deuterons. There are several methods for the production of 109 Cd in literature: 1. In the nuclear medicine field there is growing interest in employing 109 Cd in a 109 Cd/ 109mA g generator, as an alternative to other biomedical generators of ultra short-lived gamma emitters. Other applications range from its use as an electron source for measurement of densities of air-pollution samples, to tracer studies in mushrooms and mice and rats. This radionuclide has found widespread use as a photon source in x-ray fluorescence analysis devices employed in industry for numerous applications such as the direct determination of gold in ores, the analysis of metals and identification of steels. Rakhmanov, A.įull text: Cadmium- 109 has a half-life of 461.9 days and decays by electron capture to 109 Ag with the emission of 88 keV Î³-ray (3.79%) along with the characteristic X-ray from the K level of Ag, with energy of 22.5 keV. International Nuclear Information System (INIS)Įgamediev, S.

Bun normal range 110.77